Hozumi Motohashi : rechercher sur Z-Library

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1

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

Kobayashi, Eri H., Suzuki, Takafumi, Funayama, Ryo, Nagashima, Takeshi, Hayashi, Makiko, Sekine, Hiroki, Tanaka, Nobuyuki, Moriguchi, Takashi, Motohashi, Hozumi, Nakayama, Keiko, Yamamoto, Masayuki

Journal:

Nature Communications

Année:

2016

Langue:

english

Fichier:

PDF, 970 KB

english, 2016

2

Identification of polymorphisms in the promoter region of the human NRF2 gene

Tae Yamamoto, Keigyou Yoh, Akira Kobayashi, Yukio Ishii, Shigeo Kure, Akio Koyama, Tohru Sakamoto, Kiyohisa Sekizawa, Hozumi Motohashi, Masayuki Yamamoto

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 545 KB

english, 2004

3

Bright and dark sides of KEAP1-NRF2 system in carcinogenesis

Motohashi, Hozumi, Ida, Tomoaki, Alam, Md. Morshedul, Kitamura, Hiroshi, Akaike, Takaaki

Journal:

Free Radical Biology and Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 44 KB

english, 2018

4

From germ cells to neonates: the beginning of life and the KEAP1–NRF2 system

Matsumaru, Daisuke, Motohashi, Hozumi

Journal:

Journal of Biochemistry

Année:

2019

Langue:

english

Fichier:

PDF, 327 KB

english, 2019

5

Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy

Haruo Ohtani, Hozumi Motohashi, Hiroshi Sato, Motoharu Seiki, Hiroshi Nagura

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 936 KB

english, 1996

6

Mesodermal- vs. neuronal-specific expression of MafK is elicited by different promoters

Hozumi Motohashi, Kazuhiko Igarashi, Kou Onodera, Satoru Takahashi, Haruo Ohtani, Masato Nakafuku, Makoto Nishizawa, James Douglas Engel, Masayuki Yamamoto

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 4.33 MB

english, 1996

7

A core region of the mafK gene IN promoter directs neurone-specific transcription in vivo

Hozumi Motohashi, Jun Ohta, James Douglas Engel, Masayuki Yamamoto

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 2.75 MB

english, 1998

8

Transgenic over-expression of MafK suppresses T cell proliferation and function in vivo

Keigyou Yoh, Takehiko Sugawara, Hozumi Motohashi, Yousuke Takahama, Akio Koyama, Masayuki Yamamoto, Satoru Takahashi

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2001

9

Carcinogenesis and transcriptional regulation through Maf recognition elements

Hozumi Motohashi, Masayuki Yamamoto

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 269 KB

english, 2007

10

Evaluation of MafG interaction with Maf recognition element arrays by surface plasmon resonance imaging technique

Motoki Kyo, Tae Yamamoto, Hozumi Motohashi, Terue Kamiya, Toshihiro Kuroita, Toshiyuki Tanaka, James Douglas Engel, Bunsei Kawakami, Masayuki Yamamoto

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 299 KB

english, 2004

11

Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements

Tae Yamamoto, Motoki Kyo, Terue Kamiya, Toshiyuki Tanaka, James Douglas Engel, Hozumi Motohashi, Masayuki Yamamoto

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2006

12

Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution

Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 660 KB

english, 2011

13

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

Wakabayashi, Nobunao, Itoh, Ken, Wakabayashi, Junko, Motohashi, Hozumi, Noda, Shuhei, Takahashi, Satoru, Imakado, Sumihisa, Kotsuji, Tomoe, Otsuka, Fujio, Roop, Dennis R

Journal:

Nature Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2003

14

MafB as a type I interferon rheostat

Motohashi, Hozumi, Igarashi, Kazuhiko

Journal:

Nature Immunology

Année:

2010

Langue:

english

Fichier:

PDF, 869 KB

english, 2010

15

Solution structure of the DNA-binding domain of MafG

Kusunoki, Hideki, Motohashi, Hozumi, Katsuoka, Fumiki, Morohashi, Akio, Yamamoto, Masayuki, Tanaka, Toshiyuki

Journal:

Natural Structural Biology

Année:

2002

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2002

16

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

Yoichiro Mitsuishi, Keiko Taguchi, Yukie Kawatani, Tatsuhiro Shibata, Toshihiro Nukiwa, Hiroyuki Aburatani, Masayuki Yamamoto, Hozumi Motohashi

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 2.21 MB

english, 2012

17

Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

Nishida, Motohiro, Sawa, Tomohiro, Kitajima, Naoyuki, Ono, Katsuhiko, Inoue, Hirofumi, Ihara, Hideshi, Motohashi, Hozumi, Yamamoto, Masayuki, Suematsu, Makoto, Kurose, Hitoshi, van der Vliet, Albert,

Journal:

Nature Chemical Biology

Année:

2012

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2012

18

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity

Hiromi Okawa, Hozumi Motohashi, Akira Kobayashi, Hiroyuki Aburatani, Thomas W. Kensler, Masayuki Yamamoto

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 579 KB

english, 2006

19

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice

Tomonori Hosoya, Nobuhiko Harada, Junsei Mimura, Hozumi Motohashi, Satoru Takahashi, Osamu Nakajima, Masanobu Morita, Shimako Kawauchi, Masayuki Yamamoto, Yoshiaki Fujii-Kuriyama

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 618 KB

english, 2008

20

Inducible disruption of autophagy in the lung causes airway hyper-responsiveness

Daisuke Inoue, Hiroshi Kubo, Keiko Taguchi, Takashi Suzuki, Masaaki Komatsu, Hozumi Motohashi, Masayuki Yamamoto

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 927 KB

english, 2011

21

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system

Kai Takaya, Takafumi Suzuki, Hozumi Motohashi, Ko Onodera, Susumu Satomi, Thomas W. Kensler, Masayuki Yamamoto

Journal:

Free Radical Biology and Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2012

22

Nrf2–Keap1 defines a physiologically important stress response mechanism

Hozumi Motohashi, Masayuki Yamamoto

Journal:

Trends in Molecular Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 284 KB

english, 2004

23

O68. Physiological role of Keap1 S-guanylation by 8-nitroguanosine 3′,5′-cyclic monophosphate formed in C6 glioma cells

Shigemoto Fujii, Tomohiro Sawa, Tatsuya Okamoto, Hideshi Ihara, Hozumi Motohashi, Masayuki Yamamoto, Takaaki Akaike

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 59 KB

english, 2008

24

P78. Nitric oxide-dependent sulfhydryl modification of Keap1 by 8-nitroguanosine 3′,5′-cyclic monophosphate

Tomohiro Sawa, Shigemoto Fujii, Atsushi Irie, Tatsuya Okamoto, Hozumi Motohashi, Masayuki Yamamoto, Takaaki Akaike

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 45 KB

english, 2008

25

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

Akira Uruno, Hozumi Motohashi

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 701 KB

english, 2011

26

Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse

Shuhei Noda, Nobuhiko Harada, Azumi Hida, Yoshiaki Fujii-Kuriyama, Hozumi Motohashi, Masayuki Yamamoto

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 248 KB

english, 2003

27

Positive or Negative MARE-Dependent Transcriptional Regulation Is Determined by the Abundance of Small Maf Proteins

Hozumi Motohashi, Fumiki Katsuoka, Jordan A Shavit, James Douglas Engel, Masayuki Yamamoto

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 665 KB

english, 2000

28

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

Hozumi Motohashi, Tania O'Connor, Fumiki Katsuoka, James Douglas Engel, Masayuki Yamamoto

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 540 KB

english, 2002

29

Effect of acoustic overstimulation on regulation of glucocorticoid receptor mRNA in the cochlea of the guinea pig

Tsumoru Terunuma, Akira Hara, Masamitsu Senarita, Hozumi Motohashi, Jun Kusakari

Journal:

Hearing Research

Année:

2001

Langue:

english

Fichier:

PDF, 247 KB

english, 2001

30

Toward clinical application of the Keap1–Nrf2 pathway

Suzuki, Takafumi, Motohashi, Hozumi, Yamamoto, Masayuki

Journal:

Trends in Pharmacological Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 935 KB

english, 2013

31

Electron microscopy of primary cell cultures in solution and correlative optical microscopy using ASEM

Hirano, Kazumi, Kinoshita, Takaaki, Uemura, Takeshi, Motohashi, Hozumi, Watanabe, Yohei, Ebihara, Tatsuhiko, Nishiyama, Hidetoshi, Sato, Mari, Suga, Mitsuo, Maruyama, Yuusuke, Tsuji, Noriko M., Yamamo

Journal:

Ultramicroscopy

Année:

2014

Langue:

english

Fichier:

PDF, 10.67 MB

english, 2014

32

Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells

Murakami, Shohei, Shimizu, Ritsuko, Romeo, Paul-Henri, Yamamoto, Masayuki, Motohashi, Hozumi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.94 MB

english, 2014

33

Dysgenesis of melanocytes and cochlear dysfunction in mutant microphthalmia (mi) mice

Motohashi, Hozumi, Hozawa, Koji, Oshima, Takeshi, Takeuchi, Takuji, Takasaka, Tomonori

Journal:

Hearing Research

Année:

1994

Langue:

english

Fichier:

PDF, 1.79 MB

english, 1994

34

GATA-1 Transcription is Controlled by Distinct Regulatory Mechanisms during Primitive and Definitive Erythropoiesis

Ko Onodera, Satoru Takahashi, Shigeko Nishimura, Jun Ohta, Hozumi Motohashi, Kentaro Yomogida, Norio Hayashi, James Douglas Engel and Masayuki Yamamoto

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.68 MB

english, 1997

35

NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

Shirasaki, Keiichi, Taguchi, Keiko, Unno, Michiaki, Motohashi, Hozumi, Yamamoto, Masayuki

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2014

36

Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice

Hirotsu, Yosuke, Higashi, Chika, Fukutomi, Toshiaki, Katsuoka, Fumiki, Tsujita, Tadayuki, Yagishita, Yoko, Matsuyama, Yuka, Motohashi, Hozumi, Uruno, Akira, Yamamoto, Masayuki

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2014

37

MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism

de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Ahn, Hannah, Hagey, Lee R., Romanoski, Casey E., Lee, Richard G., Graham, Mark J., Motohashi, Hozumi, Yamamoto, Masayuki, Edwards, Peter A.

Journal:

Cell Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2015

38

Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element

Katsuoka, Fumiki, Motohashi, Hozumi, Engel, James Douglas, Yamamoto, Masayuki

Journal:

Journal of Biological Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 946 KB

english, 2005

39

Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract

Agrawal, Smriti A., Anand, Deepti, Siddam, Archana D., Kakrana, Atul, Dash, Soma, Scheiblin, David A., Dang, Christine A., Terrell, Anne M., Waters, Stephanie M., Singh, Abhyudai, Motohashi, Hozumi, Y

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.96 MB

english, 2015

40

The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism

Mitsuishi, Yoichiro, Motohashi, Hozumi, Yamamoto, Masayuki

Journal:

Frontiers in Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 1003 KB

english, 2012

41

Roles of NRF2 in cell proliferation and differentiation

Murakami, Shohei, Motohashi, Hozumi

Journal:

Free Radical Biology and Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2015

42

Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo

Ota, Chiharu, Yamada, Mitsuhiro, Fujino, Naoya, Motohashi, Hozumi, Tando, Yukiko, Takei, Yusuke, Suzuki, Takaya, Takahashi, Toru, Kamata, Satoshi, Makiguchi, Tomonori, Yamaya, Mutsuo, Kubo, Hiroshi

Journal:

Experimental Lung Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2015

43

Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer from that of Maf homodimer.

Kimura, Momoko, Yamamoto, Tae, Zhang, Jianyong, Itoh, Ken, Kyo, Motoki, Kamiya, Terue, Aburatani, Hiroyuki, Katsuoka, Fumiki, Kurokawa, Hirofumi, Tanaka, Toshiyuki, Motohashi, Hozumi, Yamamoto, Masayu

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 238 KB

english, 2015

44

Whole-body in vivo monitoring of inflammatory diseases exploiting human interleukin 6-luciferase transgenic mice

Hayashi, Makiko, Takai, Jun, Yu, Lei, Motohashi, Hozumi, Moriguchi, Takashi, Yamamoto, Masayuki

Journal:

Molecular and Cellular Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2015

45

An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease

Anand, Deepti, Agrawal, Smriti A., Siddam, Archana D., Motohashi, Hozumi, Yamamoto, Masayuki, Lachke, Salil A.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 875 KB

english, 2015

46

Syndecan 4 Mediates Nrf2-dependent Expansion of Bronchiolar Progenitors That Protect Against Lung Inflammation

Santoso, Arif, Kikuchi, Toshiaki, Tode, Naoki, Hirano, Taizou, Komatsu, Riyo, Damayanti, Triya, Motohashi, Hozumi, Yamamoto, Masayuki, Kojima, Tetsuhito, Uede, Toshimitsu, Nukiwa, Toshihiro, Ichinose,

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2015

47

The Transcription Factor Bach2 is Phosphorylated at Multiple Sites in Murine B Cells But a Single Site Prevents Its Nuclear Localization

Ando, Ryo, Shima, Hiroki, Tamahara, Toru, Sato, Yoshihiro, Watanabe-Matsui, Miki, Kato, Hiroki, Sax, Nicolas, Motohashi, Hozumi, Taguchi, Keiko, Yamamoto, Masayuki, Nio, Masaki, Maeda, Tatsuya, Ochiai

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 8.85 MB

english, 2015

48

Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis

Goto, Maki, Kitamura, Hiroshi, Alam, Md. Morshedul, Ota, Nao, Haseba, Takeshi, Akimoto, Toshio, Shimizu, Akio, Takano-Yamamoto, Teruko, Yamamoto, Masayuki, Motohashi, Hozumi

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 2.96 MB

english, 2015

49

Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides

Fujii, Shigemoto, Sawa, Tomohiro, Nishida, Motohiro, Ihara, Hideshi, Ida, Tomoaki, Motohashi, Hozumi, Akaike, Takaaki

Journal:

Archives of Biochemistry and Biophysics

Année:

2016

Langue:

english

Fichier:

PDF, 632 KB

english, 2016

50

Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes

Zhang, Jianyong, Hosoya, Tomonori, Maruyama, Atsushi, Nishikawa, Keizo, Maher, Jonathan M., Ohta, Tsutomu, Motohashi, Hozumi, Fukamizu, Akiyoshi, Shibahara, Shigeki, Itoh, Ken, Yamamoto, Masayuki

Journal:

Biochemical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 654 KB

english, 2007